Growth and differentiation factor-11 is developmentally regulated in skeletal muscle and inhibits myoblast differentiation

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Growth and differentiation factor-11 is developmentally regulated in skeletal muscle and inhibits myoblast differentiation

Growth and differentiation factor-11 (GDF-11) is a secreted protein that is closely related to myostatin, a known inhibitor of skeletal muscle development. The role of GDF-11 in regulating skeletal muscle growth remains unclear and the pattern of expression during post-natal growth has not been reported. Therefore, we sought to determine the expression of GDF-11 during post-natal growth and its...

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Dynamics of the skeletal muscle secretome during myoblast differentiation.

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ژورنال

عنوان ژورنال: Open Journal of Molecular and Integrative Physiology

سال: 2012

ISSN: 2162-2159,2162-2167

DOI: 10.4236/ojmip.2012.24018